Volume 27, Issue 4 (2024)
mjms 2024, 27(4): 39-43 |
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Jadidi P, Mohammadi M. Brief review of deep brain stimulation anticonvulsant mechanisms in epilepsy. mjms 2024; 27 (4) :39-43
URL: http://mjms.modares.ac.ir/article-30-78892-en.html
URL: http://mjms.modares.ac.ir/article-30-78892-en.html
1- Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
2- Department of Biophysics, Institute of Biophysics and Biochemistry, University of Tehran, Tehran, Iran ,mohammadi.mahtab@ut.ac.ir
2- Department of Biophysics, Institute of Biophysics and Biochemistry, University of Tehran, Tehran, Iran ,
Abstract: (233 Views)
Deep Brain Stimulation (DBS) has been developed as a new therapeutic manner for the treatment of neurological disorders, offering a reversible and adjustable alternative to traditional lesion-based surgeries. By delivering targeted electrical stimulation to specific brain regions, DBS modulates neural circuits and restores dysfunctional networks. Beyond its established role in movement disorders like Parkinson’s disease, DBS has shown remarkable efficacy in managing epilepsy. Its therapeutic effects are mediated through complex mechanisms, including neurotransmitter modulation, ion channel regulation, and alterations in the brain’s microenvironment. This article explores how DBS leverages these multifaceted processes to revolutionize neuromodulation and offers insights into its expanding potential for treating epilepsy.
Keywords: Deep Brain Stimulation, Epilepsy, Anticonvulsant, Seizure
Keywords: Deep Brain Stimulation, Epilepsy, Anticonvulsant, Seizure
Article Type: Systematic Review |
Subject:
Neuroscience (General)
Received: 2025/01/7 | Accepted: 2025/01/24
Received: 2025/01/7 | Accepted: 2025/01/24
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