Effect of Alzheimer’s disease on synaptic activity and functional connectivity

Document Type : Systematic Review

Authors
S. R. Eftekhari 1
N. Heidari 2
M. Rezaei 3
1 Department of Modern Technology in Biological and Medical Sciences, Faculty of Interdisciplinary Sciences and Technology, Tarbiat Modares University, Tehran, Iran
2 Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
3 Phd of Medical Physiology
Abstract
Alzheimer's is a neurodegenerative disorder characterized by memory impairment and learning difficulties. Alzheimer's disease is recognized as the most common cause of memory loss and dementia in middle-aged and elderly individuals, and it is the fifth leading cause of death among the elderly. Extensive research is being conducted to identify the causes and pathological mechanisms involved in this disease, as a proper understanding of these mechanisms could lead to the discovery of fundamental treatments. In this article, we have looked at some of the pathological mechanisms of this disease, which result from changes in synaptic function and functional connectivity.

Keywords

Subjects

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Pathobiology Reserach
Volume 26, Issue 3
September 2023
Pages 25-30