A Review of Exosome-Mediated Immunotherapy in Iran

Document Type : Analytic Review

Author
M. Soleimani
Department of Hematology , Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran Medical Nanotechnology and Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract
For decades, chemotherapy and radiotherapy have been considered the two main pillars of cancer treatment, but with the advent of immunotherapy, studies have been shifted towards this treatment method. The main goal of immunotherapy is to strengthen or support the patient's immune system in destroying malignant cells. From the first immunotherapy in 1981 to 2013, when immunotherapy was introduced as the "Scientific Achievement of the Year," various immunotherapy methods have been used to treat patients. Since the use of cells in therapy has always been associated with problems, the introduction of exosomes as nanoparticles that could easily reach the target tissue could greatly overcome the challenges of immunotherapy. In this review, we aimed to review studies on exosome-mediated immunotherapy. Although the studies have been shown favorable outcomes, it would be valuable to conduct research in this field that could help to better advance and solve the challenges of exosome mediated immunotherapy.

Keywords

Subjects

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Pathobiology Reserach
Volume 27, Issue 3
November 2024
Pages 31-39