Comparison liver and kidney functions among COVID-19 infected patients, recovery period, and healthy subjects

Document Type : Original Research

Authors
N. T. yassin 1
M. abbasnejad 1
S. Esmaeili-Mahani 2
1 Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran
2 1 Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran2 Laboratory of Molecular Neuroscience, Kerman Neuroscience Research Center (KNRC), Kerman University of Medical Sciences, Kerman, Iran
Abstract
Introduction: Corona damage a wide range of organs and their functions So, the purpose of this study is to compare the function of kidneys and livers in COVID-19-infected people and people who were in the recovery phase after about five months from the onset of the infection.

Methods: This study was carried out in Samarra General Hospital (COVID-19 epidemic center) in Salahuddin province Iraq from the 1st of January 2022 till the end of December 2022. In The case-control study 100 subjects (men and women 20-80 years), 40 adult people as control with negative RT-PCR or CT-Scan for COVID-19 and no apparent chronic diseases, and 60 subjects (n=30). The blood urea, creatinine as markers of kidney function, ALT, AST, alkaline phosphatase, and C-reactive protein as markers of liver function by special kits were assessed.

Results: In COVID-19-infected subjects and in subjects in the recovery stage, the markers of kidney function, blood urea, and creatinine increased significantly (p<0.001), and in this regard, no difference was seen between the two genders. Similarly, the evaluation of compounds related to liver function, including ALT, AST, alkaline phosphatase, and C-reactive protein, was significantly higher in both affected and recovering patients (p<0.001) compared to healthy individuals. In this case, there was no difference between the two genders.

Conclusion: It seems that not only in COVID-19-infected subjects but also in subjects who have recovered from corona, in both men and women, there are relatively permanent failures in the function of kidneys and liver.

Keywords

Subjects

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Pathobiology Reserach
Volume 27, Issue 3
November 2024
Pages 47-53