Investigation of HPV Type 16/18 as a Risk Marker in the Gastric Carcinoma Patients Ardabil Province

Document Type : Original Research

Authors
K. Radjabalizadeh 1
F. Seyyed younesi 2
1 Department of Biology, Ardabil branch, Islamic Azad University, Ardabil, Iran
2 Department of biology, Ardabil branch, Islamic Azad University, Ardabil, Iran
Abstract
introduction: Several risk factors for gastric carcinoma have been suggested, and human papillomavirus (HPV) infection is one of them. This virus, with more than 100 genotypes, is in the Papillomaviridae family. The present study was conducted to investigate the prevalence of human papillomavirus types 16 and 18 in gastric carcinoma patients in the Ardabil province.

Methods: This study is a case-control study in which 50 patients with stomach cancer and 50 healthy individuals were tested for papillomavirus type 16 and 18 DNA in their blood samples after DNA extraction by polymerase chain reaction (PCR).

Results: In the study conducted, the frequency of healthy men and women was 46% and 54%, respectively, and in sick people, it was 66% and 34%. The present study showed that in the population of Ardabil province, the frequency of human papillomavirus types 16 and 18 in gastric carcinoma patients was zero.

Conclusion: The current study on human papillomavirus types 16 and 18 in patients with gastric cancer shows a very low frequency in the population of Ardabil province.

Keywords

Subjects

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Pathobiology Reserach
Volume 27, Issue 4
December 2024
Pages 15-22