Volume 8, Issue 1 (2006)                   mjms 2006, 8(1): 45-54 | Back to browse issues page

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Oloumi M M, Derakhshanfar A, Dabbaghian A. Histopathologic and biomechanical comparisons of the properties of skin, sutured with an Iranian and a foreign brand silk suture in rat. mjms 2006; 8 (1) :45-54
URL: http://mjms.modares.ac.ir/article-30-7839-en.html
1- Associate Professor of Veterinary Surgery, Department of Clinical Sciences, Faculty of veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran.
2- Associate Professor of Veterinary Pathology, Department of Pathobiology, Faculty of veterinary Medicine, Shahic Bahonar University of Kerman, Kerman, Iran
3- Doctor of Veterinary Medicine Graduate, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran
Abstract:   (4575 Views)
Purpose: Since there have been some debates about using Supa brand silk, this study was designed to elucidate the possible differences between Supa and Ethicon silk in suturing rat skin. Materials & Methods: This study was carried out on 60 female Spragne-Dawly albino rats. The animals were randomly assigned to two equal groups. In group one, 3/0 silk, Supa product, and in group two, 3/0 silk Ethicon product were used. Following general anesthesia and surgical preparation, a 5 cm midline abdominal skin incision was made and sutured by a simple interrupted pattern. Fifteen animlas of each group were sacrificed on day 6 for the histopathologic examination and the rest of the animals, on day 13 for histopathologic and biomechanical examinations. Histopathologic sections were stained by H&E and examined under the light microscope for the re-epithelialization, acanthosis, age of granulation tissue, dermatitis, hyperemia, and presence of giant cells. Results: There was no significant differences between the two groups on day 6 and 13 (P>0.05). In the biomechanical study, the following parameters were measured from load-elongation curves: the ultimate strength, ultimate strain, yield strain, stiffness, and maximum stored energy. Regarding these factors, there was no significant differences between the groups either (P>0.05). Conclusion: According to the results of this study and considering the price and availability, using Supa silk can be recommended with confidence and reliability.
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Received: 2003/09/6 | Accepted: 2004/09/5

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