Volume 12, Issue 2 (2009)                   mjms 2009, 12(2): 37-49 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Jamali S, Emtiazjoo M, Toolabee L, Zeinali S, keypour S, Sardari S, et al . Antibacterial effect of the Persian Gulf sea cucumber Holoturia. SP extracts on three strain of Escherichia coli. mjms. 2009; 12 (2) :37-49
URL: http://mjms.modares.ac.ir/article-30-8034-en.html
1- Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
2- Department of Marine Biology, Faculty of Marine Sciences and Technology, Azad Islamic University, North Tehran Branch Tehran, Iran
3- Department of Molecular Medicine, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
4- Department of Molecular Medicine, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran Department of Genetics, Kawsar Human Genetics Research Center, Tehran, Iran
5- Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
6- Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, , Iran
7- of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
Abstract:   (4626 Views)
Objective: Sea cucumber is a traditional food and medical item and has been reported to exhibit Antioxidant, antifungal, anti tumoral and antibacterial bioactivity. The objective of this study is to describe the antibacterial activity of 4 extracts of Holoturia. Sp (sea cucumber), collected from Hengam Island of Persian Gulf. Materials and Methods: Methanol, hexane, aqueous and chloroform extracts from body wall tissue of the sea cucumber were screened for antibacterial activity against three strains of Escherichia coli Top 10 F´, TG1 and K12 using disc diffusion and broth microdilution tests methods. Result: The growth of all these strains were inhibited using concentration from 0.78 to 100 mg/ml of methanol, hexan and chloroform extracts. Among the extracts just methanol and chloroform with 100 mg/ml had bactericidal effect on TG1 and K12 strains. On the other hand, Aqueous extract had induced growth in of the all strains. Conclusion: The results suggest the possibility of applying sea cucumber as source of potential anti bacterial agents, whose compounds can be good candidates to make antibiotic products.
Full-Text [PDF 803 kb]   (5594 Downloads)    

Received: 1901/12/14 | Accepted: 1901/12/14

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.