Volume 19, Issue 4 (2017)                   mjms 2017, 19(4): 13-25 | Back to browse issues page

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Doostdar M, Fathei M, Hejazi K, Kiani gol M. The Effect of Eight Weeks of Aerobic Training on Leptin, Interlukin-6, and Tumor Necrosis Factor-alpha Levels in Inactive Elderly Women. mjms 2017; 19 (4) :13-25
URL: http://mjms.modares.ac.ir/article-30-10248-en.html
The Effect of Eight Weeks of Aerobic Training on Leptin, Interlukin-6, and Tumor Necrosis Factor-alpha Levels in Inactive Elderly Women
Mehdi Doostdar1 , Mehrdad Fathei2 , Keyvan Hejazi 2, Mojtaba Kiani gol3
1- Department of Exercise Physiology, Mashhad branch of Islamic Azad University, Mashhad, Iran
2- Department of Exercise Physiology, Ferdowsi University of Mashhad, Mashhad, Iran
3- Department of Exercise Physiology, Hakim Sabzevari University, Sabzevar, Iran
Abstract:   (9464 Views)
Objective: Atherosclerosis is the most common cause of coronary heart disease and a major cause of ischemic heart diseases. We have investigated the effect of eight weeks of aerobic training on the serum levels of leptin, IL-6, and TNF-α in inactive elderly women. Methods: In this semi-experimental study, participants were selected by convenience sampling. We divided 21 subjects into two groups - active (n=10) and non-active (n=11). The program training included 60 min per session, 3 times per week for 8 weeks of aerobic exercise with 50-70 HRR%. Blood samples were taken before and after 8 weeks of aerobic training. We used the t-test for dependent and independent samples for intra- and intergroup comparisons. For all statistical comparisons, the level of significance was set at P<0.05. Results: The aerobic training groups had a significant reduction in leptin (P=0.001), IL-6 (P=0.01), and TNF-α (P=0.001) after 8 weeks of aerobic training compared with the control group. The intergroup variations in weight, BMI, leptin, and TNF-α had a significant change (P<0.05). Conclusion: The results of the present study suggested that endurance training decreased leptin, IL-6, and TNF-α levels, effectively improved cardiovascular health, and reduced the risk of atherosclerosis.
Keywords: Leptin, Interlukin-6, Aerobic exercises, Elderly women
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Article Type: Original Manuscipt | Subject: Exercise Physiology
Received: 2017/02/17 | Accepted: 2017/01/20
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