Volume 22, Issue 3 (2019)                   mjms 2019, 22(3): 129-134 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Asad M, Ghadiri M, Barzegari A. Effect of sequence of combined strength and endurance training on the levels of nesfatin-1 and some metabolic risk factors of overweight women. mjms. 2019; 22 (3) :129-134
URL: http://mjms.modares.ac.ir/article-30-30670-en.html
1- Physical Education & Sport Department, Education & Psychology Faculty, Payame Noor University, Tehran, Iran , m_r_asad@pnu.ac.ir
2- Physical Education & Sport Department, Education & Psychology Faculty, Payame Noor University, Tehran, Iran
Abstract:   (5857 Views)
Aims: Nesfatin-1 is an adipokine that plays an important role in regulating appetite and energy homeostasis. The purpose of this study was to investigate the effect of sequence order of combined strength and endurance training on the levels of nesfatin-1 and some metabolic risk factors of overweight women.
Materials and Methods: In this quasi-experimental study, 30 overweight women (With a mean age of 28.00±3.17 years and BMI>25kg/m2), after initial evaluations and having the conditions for participation in the research, were randomly divided into 3 endurance-strength training groups (E+S; 10), strength-endurance training (S+E; 10) and overweight control (10). Experimental groups performed endurance and strength training for 8 weeks, 3 sessions each week and each session for 1 hour. Levels of nesfatin-1, insulin, glucose, and Insulin resistance before running the protocol and 48 hours after the last training session was measured by ELISA. To analyze the data, One-way ANOVA were used at a significance level of p≤0.05.
Findings: The results showed that in the comparison between the group, the combination of strength and resistance training increased the levels of nesfatin-1 significantly (p=0.009) and a significant reduction in glucose levels (p=0.009), insulin resistance (p=0.001) and insulin (p=0.001) was also observed.
Conclusion: According to the results, strength and endurance combined exercises can be effective on levels of metabolic indexes and leads to a decrease in metabolic risk indicators. Strength-endurance training seems to have more beneficial effects on the improvement of metabolic indexes.
 
Full-Text [PDF 766 kb]   (1315 Downloads)    
Article Type: Original Research | Subject: Sport physiology
Received: 2019/02/22 | Accepted: 2019/06/12

References
1. Church C, Moir L, Mc Murray F, Girard C, Banks GT, Teboul L, et al. Overexpression of Fto leads to increased food intake and results in obesity. Nat Genet. 2010;42(12):1086-92. [Link] [DOI:10.1038/ng.713]
2. Ghanbari Niaki A, Fathi R, Ramroudi S, Hedayati M. Effect of 8 weeks endurance training with two different durations on plasma HDL-ghrelin in male rats. Iran J Endocrinol Metab. 2011;13(3):309-14. [Persian] [Link]
3. Williams G, Bing C, Cai XJ, Harrold JA, King PJ, Liu XH. The hypothalamus and the control of energy homeostasis: Different circuits, different purposes. Physiol Behav. 2001;74(4-5):683-701. [Link] [DOI:10.1016/S0031-9384(01)00612-6]
4. Tofighi A, Mehrabani J, Khadivi SM. The effect of 8 week aerobic exercise on nesfatin-1 and acylated ghrelin in young obese men. Med J Mashhad Univ Med Sci. 2014;57(3):562-70. [Persian] [Link]
5. Taji Tabas A, Mogharnasi M. The effect of 10 week resistance exercise training on serum levels of nesfatin-1 and insulin resistance index in woman with type 2 diabetes. Iran J Diabetes Metab. 2016;14(3):179-88. [Persian] [Link]
6. Stengel A, Goebel M, Wang L, Taché Y. Ghrelin, des-acyl ghrelin and nesfatin-1 in gastric X/A-like cells: Role as regulators of food intake and body weight. Peptides. 2010;31(2):357-69. [Link] [DOI:10.1016/j.peptides.2009.11.019]
7. Haghshenas R, Jafari M, Ravasi AA, Kordi MR, Gilani N, Shariatzadeh M, et al. The effect of eight weeks endurance training and high-fat diet on appetite-regulating hormones in rat plasma. Iran J Basic Med Sci. 2014;17(4):237-43. [Link]
8. Tsuchiya T, Shimizu H, Yamada M, Osaki A, Oh-I S, Ariyama Y, et al. Fasting concentrations of nesfatin-1 are negatively correlated with body mass index in non-obese males. Clin Endocrinol (Oxf). 2010;73(4):484-90. [Link] [DOI:10.1111/j.1365-2265.2010.03835.x]
9. Churilla JR, Zoeller Jr RF. Physical activity: Physical activity and the metabolic syndrome: A review of the evidence. Am J Lifestyle Med. 2008;2(2):118-25. [Link] [DOI:10.1177/1559827607311981]
10. Lakka TA, Laaksonen DE. Physical activity in prevention and treatment of the metabolic syndrome. Appl Physiol Nutr Metab. 2007;32(1):76-88. [Link] [DOI:10.1139/h06-113]
11. Lakka TA, Laaksonen DE, Lakka HM, Männikkö N, Niskanen LK, Rauramaa R, et al. Sedentary lifestyle, poor cardiorespiratory fitness, and the metabolic syndrome. Med Sci Sports Exerc. 2003;35(8):1279-86. [Link] [DOI:10.1249/01.MSS.0000079076.74931.9A]
12. Ardern CI, Janssen I. Metabolic syndrome and its association with morbidity and mortality. Appl Physiol Nutr Metab. 2007;32(1):33-45. [Link] [DOI:10.1139/h06-099]
13. Azizi F, Salehi P, Etemadi A, Zahedi Asl S. Prevalence of metabolic syndrome in an urban population: Tehran lipid and glucose study. Diabetes Res Clin Pract. 2003;61(1):29-37. [Link] [DOI:10.1016/S0168-8227(03)00066-4]
14. Su Y, Zhang J, Tang Y, Bi F, Liu JN. The novel function of nesfatin-1: Anti-hyperglycemia. Biochem Biophys Res Commun. 2010;391(1):1039-42. [Link] [DOI:10.1016/j.bbrc.2009.12.014]
15. Rennie KL, Mc Carthy N, Yazdgerdi S, Marmot M, Brunner E. Association of the metabolic syndrome with both vigorous and moderate physical activity. Int J Epidemiol. 2003;32(4):600-6. [Link] [DOI:10.1093/ije/dyg179]
16. De Groot PC, Hjeltnes N, Heijboer AC, Stal W, Birkeland K. Effect of training intensity on physical capacity, lipid profile and insulin sensitivity in early rehabilitation of spinal cord injured individuals. Spinal Cord. 2003;41(12):673-9. [Link] [DOI:10.1038/sj.sc.3101534]
17. Chaolu H, Asakawa A, Ushikai M, Li YX, Cheng KC, Li JB, et al. Effect of exercise and high-fat diet on plasma adiponectin and nesfatin levels in mice. Exp Ther Med. 2011;2(2):369-73. [Link] [DOI:10.3892/etm.2011.199]
18. Bashiri J, Gholami F, Rahbaran A, Tarmahi V. Effect of single bout of aerobic exercise on serum nesfatin-1 levels in non-athlete elderly men. Med J Tabriz Univ Med Sci. 2012;34(4):25-30. [Persian] [Link]
19. Valizadeh A, Azmoon HR. The effect of eight weeks of strength, endurance and concurrent training programs on the upper and lower body strength. Fiziceskoe Vospitanie Studentov. 2012;4:135-39. [Link]
20. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412-9. [Link] [DOI:10.1007/BF00280883]
21. Essig DA, Alderson NL, Ferguson MA, Bartoli WP, Durstine JL. Delayed effects of exercise on the plasma leptin concentration. Metabolism. 2000;49(3):395-9. [Link] [DOI:10.1016/S0026-0495(00)90396-2]
22. Magkos F, Tsekouras Y, Kavouras SA, Mittendorfer B, Sidossis LS. Improved insulin sensitivity after a single bout of exercise is curvilinearly related to exercise energy expenditure. Clin Sci (Lond) 2008; 114(1):59-64. [Link] [DOI:10.1042/CS20070134]
23. Gonzalez R, Perry RL, Gao X, Gaidhu MP, Tsushima RG, Ceddia RB, et al. Nutrient responsive nesfatin-1 regulates energy balance and induces glucose-stimulated insulin secretion in rats. Endocrinology. 2011;152(10):3628-37. [Link] [DOI:10.1210/en.2010-1471]
24. Miller RA, Buehner G, Chang Y, Harper JM, Sigler R, Smith-Wheelock M. Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance. Aging Cell. 2005;4(3):119-25. [Link] [DOI:10.1111/j.1474-9726.2005.00152.x]
25. Davidson LE, Hudson R, Kilpatrick K, Kuk JL, Mc Millan K, Janiszewski PM, et al. Effects of exercise modality on insulin resistance and functional limitation in older adults: A randomized controlled trial. Arch Intern Med. 2009;169(2):122-31. [Link] [DOI:10.1001/archinternmed.2008.558]
26. Jorge ML, De Oliveira VN, Resende NM, Paraiso LF, Calixto A, Diniz AL, et al. The effects of aerobic, resistance, and combined exercise on metabolic control, inflammatory markers, adipocytokines, and muscle insulin signaling in patients with type 2 diabetes mellitus. Metabolism. 2011;60(9):1244-52. [Link] [DOI:10.1016/j.metabol.2011.01.006]
27. Brooks N, Layne JE, Gordon PL, Roubenoff R, Nelson ME, Castaneda-Sceppa C. Strength training improves muscle quality and insulin sensitivity in Hispanic older adults with type 2 diabetes. Int J Med Sci. 2006;4(1):19-27. [Link] [DOI:10.7150/ijms.4.19]
28. Enteshary M, Esfarjani F, Reisi J. The Comparison of 8 week combined training with two different intensity on level of serum irisin, and glycemic indices of type 2 diabetic women. Med J Mashhad Univ Med Sci. 2018;61(2):971-84. [Persian] [Link]

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.