Volume 25, Issue 4 (2022)
mjms 2022, 25(4): 43-49 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Karimi O, Hassanshahi J, Shamsizadeh A. The Role of Medicinal Plants in Treating Mild Cognitive Impairment: A Focus on Mitophagy Modulation. mjms 2022; 25 (4) :43-49
URL: http://mjms.modares.ac.ir/article-30-75990-en.html
URL: http://mjms.modares.ac.ir/article-30-75990-en.html
1- Physiology-Pharmacology Research Center, Research Institute on Basic Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
2- Department of Physiology and Pharmacology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
3- Occupational safety and health research center, NICICO, WSO and Rafsanjan University of Medical Sciences, Rafsanjan, Iran ,alishamsy@gmail.com
2- Department of Physiology and Pharmacology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
3- Occupational safety and health research center, NICICO, WSO and Rafsanjan University of Medical Sciences, Rafsanjan, Iran ,
Abstract: (1573 Views)
Mild cognitive impairment (MCI) is a transitional stage between normal aging and dementia, characterized by cognitive decline that is more pronounced than expected for age. While the exact mechanisms underlying MCI remain elusive, mounting evidence suggests that impaired mitophagy, a cellular process responsible for removing damaged mitochondria, may contribute to its development. Medicinal plants, rich in bioactive compounds, have shown promise in treating MCI. This review explores the potential of medicinal plants to ameliorate MCI by modulating mitophagy. We delve into the intricate interplay between mitophagy dysfunction and MCI, highlighting the pathways involved. Furthermore, we examine the reported effects of various medicinal plants on mitophagy, emphasizing their potential to restore mitochondrial homeostasis and protect cognitive function. Finally, we discuss future research directions and perspectives on the therapeutic potential of medicinal plants in MCI management.
Article Type: Systematic Review |
Subject:
Behavioral Neuroscience
Received: 2024/07/8 | Accepted: 2024/07/13
Received: 2024/07/8 | Accepted: 2024/07/13
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |