Volume 27, Issue 3 (2024)
mjms 2024, 27(3): 47-53 |
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yassin N T, abbasnejad M, Esmaeili-Mahani S. Comparison liver and kidney functions among COVID-19 infected patients, recovery period, and healthy subjects. mjms 2024; 27 (3) :47-53
URL: http://mjms.modares.ac.ir/article-30-78477-en.html
URL: http://mjms.modares.ac.ir/article-30-78477-en.html
1- Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran
2- Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran ,mabbas@uk.ac.ir
3- 1 Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran2 Laboratory of Molecular Neuroscience, Kerman Neuroscience Research Center (KNRC), Kerman University of Medical Sciences, Kerman, Iran
2- Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran ,
3- 1 Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran2 Laboratory of Molecular Neuroscience, Kerman Neuroscience Research Center (KNRC), Kerman University of Medical Sciences, Kerman, Iran
Abstract: (95 Views)
Introduction: Corona damage a wide range of organs and their functions So, the purpose of this study is to compare the function of kidneys and livers in COVID-19-infected people and people who were in the recovery phase after about five months from the onset of the infection.
Methods: This study was carried out in Samarra General Hospital (COVID-19 epidemic center) in Salahuddin province Iraq from the 1st of January 2022 till the end of December 2022. In The case-control study 100 subjects (men and women 20-80 years), 40 adult people as control with negative RT-PCR or CT-Scan for COVID-19 and no apparent chronic diseases, and 60 subjects (n=30). The blood urea, creatinine as markers of kidney function, ALT, AST, alkaline phosphatase, and C-reactive protein as markers of liver function by special kits were assessed.
Results: In COVID-19-infected subjects and in subjects in the recovery stage, the markers of kidney function, blood urea, and creatinine increased significantly (p<0.001), and in this regard, no difference was seen between the two genders. Similarly, the evaluation of compounds related to liver function, including ALT, AST, alkaline phosphatase, and C-reactive protein, was significantly higher in both affected and recovering patients (p<0.001) compared to healthy individuals. In this case, there was no difference between the two genders.
Conclusion: It seems that not only in COVID-19-infected subjects but also in subjects who have recovered from corona, in both men and women, there are relatively permanent failures in the function of kidneys and liver.
Methods: This study was carried out in Samarra General Hospital (COVID-19 epidemic center) in Salahuddin province Iraq from the 1st of January 2022 till the end of December 2022. In The case-control study 100 subjects (men and women 20-80 years), 40 adult people as control with negative RT-PCR or CT-Scan for COVID-19 and no apparent chronic diseases, and 60 subjects (n=30). The blood urea, creatinine as markers of kidney function, ALT, AST, alkaline phosphatase, and C-reactive protein as markers of liver function by special kits were assessed.
Results: In COVID-19-infected subjects and in subjects in the recovery stage, the markers of kidney function, blood urea, and creatinine increased significantly (p<0.001), and in this regard, no difference was seen between the two genders. Similarly, the evaluation of compounds related to liver function, including ALT, AST, alkaline phosphatase, and C-reactive protein, was significantly higher in both affected and recovering patients (p<0.001) compared to healthy individuals. In this case, there was no difference between the two genders.
Conclusion: It seems that not only in COVID-19-infected subjects but also in subjects who have recovered from corona, in both men and women, there are relatively permanent failures in the function of kidneys and liver.
Article Type: Original Research |
Subject:
Viral pathogenesis
Received: 2024/12/15 | Accepted: 2024/12/21
Received: 2024/12/15 | Accepted: 2024/12/21
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